Freddy Boey, Subbu Venkatraman

Nanyang Technological University, 50 Nanyang Avenue Singapore 639798, Singapore

Controlled Local Drug Release through the use of Biodegradable Biomaterials has recently been shown to be a highly efficacious method for therapeutic treatment of diseases. This presentation shares the results of both the research and the commercialization aspects of some devices developed in Nanyang Technological University (NTU), l which has led to a funded startup company each. The first is the development of a fully biodegradable multi layered and drug eluting biopolymer stent for treating coronary artery blockages. The company has successfully carried out Phase 2 human trials and has attracted a buy in from a major Biomedical Device company, Boston Scientific. The second is the development of a first ever injected nanoliposome that elutes Latanoprost locally, which has been successfully shown to continuously reduce the Intra Occular Pressure for up to 6 months in its first human trials. The technology has since led to a funded startup company with funding towards Phase 2 clinical trials.